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This article is about the standard antipoison. For the item brewed within the Chambers of Xeric, see Antipoison potion.
Antipoison(1) detail.png
Antipoison(2) detail.png
Antipoison(3) detail.png
Antipoison(4) detail.png

An antipoison is a potion made by using unicorn horn dust on a marrentill potion (unf), requiring 5 Herblore, yielding an antipoison(3) and 37.5 Herblore experience. A dose of antipoison cures poison and provides immunity to poison for 90 seconds. The next cheapest alternative, superantipoison, cures poison and provides immunity to poison for 6 minutes.

After Barbarian Herblore Training, roe or caviar can be added to an antipoison(2), requiring 6 Herblore, yielding an antipoison mix and 12 Herblore experience. An antipoison mix has 2 doses, cures poison and provides immunity to poison for 90 seconds, and heals 3 Hitpoints.

An antipoison(1) spawn can be found in a chest in the Observatory Dungeon north-east of the stairs leading up to the Observatory.

An antipoison(3) can be purchased from The Spice Is Right for 432 coins, Jiminua's Jungle Store for 432 coins, or 374 coins when wearing any tier of Karamja gloves.

An antipoison(4) can be purchased from the Apothecary in Varrock for 5 coins, a cadava berry, and a limpwurt root.

An antipoison(4) is also a reward from Jekyll and Hyde random events if a marrentill is given to Dr. Jekyll.

Antipoison(1) spawns infinitely in the chest north-east of the stairs to the Observatory.

Creation[edit | edit source]

Herblore[edit | edit source]

Herblore Herblore5 (b)37.5
Member icon.png
Ticks2 (1.2s)
Marrentill potion (unf).pngMarrentill potion (unf)187
Unicorn horn dust.pngUnicorn horn dust1207
Total Cost294

Apothecary[edit | edit source]

Free-to-play icon.png
Ticks0 (0s)
ToolsNoneFacilitiesApothecary icon.png Apothecary
Limpwurt root.pngLimpwurt root1769
Cadava berries.pngCadava berries192
Total Cost861

Products[edit | edit source]

Antipoison mix(2).pngAntipoison mix(2)
Member icon.png
  • Herblore 6
  • Herblore 12

Price per dose[edit | edit source]

Item Price per dose
Antipoison(1).png Antipoison(1) 66
Antipoison(2).png Antipoison(2) 54
Antipoison(3).png Antipoison(3) 39
Antipoison(4).png Antipoison(4) 46

Item sources[edit | edit source]

Antipoison(2)[edit | edit source]

For an exhaustive list of all known sources for this item, see here (include RDT).
Maniacal Monkey Archer132 Multicombat.png12/20
Maniacal monkey140 Multicombat.png12/20

Antipoison(3)[edit | edit source]

Aviansie69–148 Multicombat.png55/128
Druid33 Multicombat.png11/128
Skeleton (Tarn's Lair) Medium level40; 63; 72; 77 Multicombat.png15/128
Spiritual mage120; 121; 123 Multicombat.png(noted)5/128

Shop locations[edit | edit source]

This list was created dynamically. For help, see the FAQ. To force an update of this list, click here.
in stock
sold at
bought at
The Spice Is Right.Sophanem201m Coins 250.png 432Coins 25.png 72Member icon.png
Jiminua's Jungle Store.Karamja101m 30sCoins 250.png 432Coins 100.png 144Member icon.png
Jiminua's Jungle Store. (Karamja gloves)Karamja101m 30sCoins 250.png 374Coins 100.png 158Member icon.png

Changes[edit | edit source]

Date Changes
3 May 2018
(update | poll)

Free-to-play players may now purchase antipoison from the Apothecary in Varrock.

15 April 2016

Half full potions could now be turned into bank placeholders.

29 March 2004

The 4 dose potion became permanently available with the launch of RuneScape 2.

9 March 2004

The 4 dose potion was added to the RuneScape 2 Beta.