The Dead Man's Chest is a bar in Brimhaven (located in northern Karamja) in which players can buy grog for 3 coins and Karamjan rum for 27 coins from the Bartender. It also plays a role in Alfred Grimhand's Barcrawl miniquest, in which the player must drink Supergrog. There are some beer and empty beer glass respawns on some of the tables. There are some barrels located by the north wall and in the south-west corner that beer glasses can be refilled at.
- Dead Man's Chest is a fictional sailor's work song from Robert Louis Stevenson's Treasure Island
- Dead Man's Chest is also a title of a sequel of Pirates' of the Caribbean, a movie released in 2006.