Disease is a status effect which can be caused by any monster found in the crypts of Jiggig, as well as fever spiders. It can also be caused by failing to pick the lock on a Zogre coffin in the Zogre dungeon or by failing to cut a scrapey tree in Trouble Brewing.
When a player has disease, shown by an orange hitsplat (), one of the player's skills, including Hitpoints, is reduced by the number on the hitsplat every eighteen seconds. Stats are restored one level every minute meaning it can take a long time to naturally recover from reduced stats.
Wearing an inoculation bracelet provides protection against the effects of disease by preventing the reduction of skill levels, but it does not cure or immunise against disease.
Curing disease[edit | edit source]
Disease will go away on its own after fifteen minutes. Skills gradually recover on their own, but for an instantaneous recovery, potions from Herblore can be used. Restore potions recover Combat skills except Prayer, while Super restore recovers all other skills and a limited amount of Prayer.
The effects of disease can be countered with Relicym's balm. Drinking one or two doses reduces the effect, while four cures most disease altogether. Instead of clicking the potion, a player may click the now-yellow hitpoints indicator to automatically drink their balm.
A Sanfew serum cures disease, and provides the player with a fifteen minute immunity to disease. Along with this it also restores prayer points, cures poison, and gives a five minute immunity to poison.
Another method is teleporting to Ferox Enclave, using a Ring of Dueling, and then using a Pool of Refreshment to restore lost stats.