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A player taking damage from poison
Poison hitpoints minimap.png

Poison is a detriment that players and monsters suffer when they are attacked by a poisonous weapon. Many NPCs are able to inflict poison. Players can use poisonous weapons or the Smoke spells from the Ancient Magicks to cause their target(s) to become poisoned. The maximum damage from this can range from 1 to over 20 depending on the type of poison.

When a player or monster is poisoned, a number appears with a green hitsplat (Poison hitsplat.png) instead of a red or blue one, indicating the amount of damage the poison has dealt. The victim is then damaged by this poison once every 18 seconds unless it is cured or it wears off. Poison wears off over time, decreasing by a value of one after every 5 hits. Poison doesn't do damage (or wear off) when a player has an interface open. It will hit once immediately after the interface is closed, and continue damaging the player every 18 seconds after that (30 game ticks).

Monsters that can inflict poison may do so regardless of whether or not they inflict any damage, even if protection prayers are used. Player inflicted poison does need to deal damage to apply.

Poison works on an internal timer, this means that NPCs with their own timers for actions like speaking can't be poisoned, even if monster examine shows they're not immune.

The list of poisons in terms of deadliness are as such:

  • Weak thieving poison by opening some thieving chests: 1-2
  • Smoke spells: 2, 4 (Rush/Burst and Blitz/Barrage respectively)
  • Various weapon poisoning (see below section): 2-6
  • Converted venom to poison by drinking any antipoison potion once: 6-20 (the same amount of damage the venom did)
  • NPC poison: (varies) 6-20. The aggressive Tribesmen of Karamja, for example, have poison starting at 11.

List of monsters[edit | edit source]

Exhaustive lists of monsters susceptible and immune to poison.

Curing poison[edit | edit source]

Poison can be cured through antidotes in the form of anti-poison potions. Anti-poison potions come in various levels, providing progressively longer immunity to becoming poisoned in addition to curing it. Players who are poisoned can use one of the following remedies or simply left-click their Hitpoints orb on the minimap and their character will automatically use a remedy that they have. Just like how poison does not damage the player with an interface opened, the antipoison timer will not go down until the interface is closed.

Those who don't have any form of cure can simply exit a player-owned house.

Name Immunity
Hourly cost Members Notes
Antipoison.png Antipoison 1.5 2,340.00 0
Free-to-play icon.png
Superantipoison.png Superantipoison 6.0 988.00 1
Member icon.png
Antidote+.png Antidote+ 9.0 3,485.00 1
Member icon.png
Antidote++.png Antidote++ 12.0 3,976.00 1
Member icon.png
Anti-venom.png Anti-venom 12.0 8,715.00 1
Member icon.png
First 18 seconds include immunity to venom
Anti-venom+.png Anti-venom+ 15.0 14,736.00 1
Member icon.png
First 3 minutes include immunity to venom
Sanfew serum.png Sanfew serum 6.0 112,378.00 1
Member icon.png
15 minutes immunity to disease
Prayer book.png Prayer book N/A N/A 1
Member icon.png
Requires prayer points
Strange fruit.png Strange fruit N/A N/A 1
Member icon.png
Guthix rest.png Guthix rest N/A N/A 1
Member icon.png
Does not cure, but reduces poison damage per hit by 1. It will downgrade venom to poison if the player is envenomed
Cure Me.png Cure Me N/A N/A 1
Member icon.png
Requires completion of Lunar Diplomacy
Cure Other.png Cure Other
Cure Group.png Cure Group
Serpentine helm.png Serpentine helm N/A 1
Member icon.png
Charged with Zulrah's scales. Provides full immunity to becoming poisoned or envenomed while worn, but does not cure preexisting poison or venom when equipped.

Weapon poisoning[edit | edit source]

Members can inflict poison by using weapons treated with weapon poisons, made primarily through the Herblore skill. There are several types of weapon poisons, which deal progressively more damage. Only spears, hastae, daggers, arrows, bolts, darts, throwing knives, and javelins can be poisoned. The abyssal tentacle and emerald bolts (e) are also capable of poisoning players. A weapon poison potion can only be used on five thrown objects before running out (e.g. 5 arrows or 5 darts). Poison can be removed from weapons by making use of a cleaning cloth, obtained by using Karamja rum with silk, by purchasing it directly from Tamayu after completing Tai Bwo Wannai Trio, or by purchasing it from the Grand Exchange for 259 coins.

A player must deal non-zero damage with the poisoned weapon to have a chance at poisoning their enemy. The chances of inflicting poison are 1/4 for melee and 1/8 for ranged and smoke spells.[1]

Name Initial damage Total damage
Melee Ranged Melee Ranged
Weapon poison.png Weapon poison 4 2 50 15
Weapon poison+.png Weapon poison+ 5 3 75 18
Weapon poison++.png Weapon poison++ 6 4 105 34
Karambwan paste (poison).png Karambwan paste (poison)[2] 6 N/A 105 N/A
Abyssal tentacle.png Abyssal tentacle 4 N/A 50 N/A
Emerald bolts (e).png Emerald bolts (e) N/A 5 N/A 75
  1. ^ Jagex. Mod Ash's Twitter account. 5 July 2017. (Archived from the original on 29 May 2020.) Mod Ash: "1/4 for melee, 1/8 for ranged. [Poison chance is] not material-dependent. Damage must be non-zero."
  2. ^ Can only be applied to spears and hastae.

The total poison damage (Melee: DM and Ranged: DR) can be calculated by the sum of all numbers (n) up to the max hit (M), times the amount of hits per number (H=5).

Notes[edit | edit source]

  • The poison's duration can be reset while the enemy is poisoned with the same chance as on an unpoisoned enemy.
  • If you poisoned a monster while fighting it, you will not receive experience from the poison damage (you will receive full Slayer experience, however, even if the poison applied wasn't yours).
  • Many monsters, such as wall beasts, turoths, waterfiends, and the God Wars Dungeon bosses, are immune to poison.
  • Poison interrupts some actions, including most skilling actions (but not Woodcutting or Fishing) and the home and minigame teleports. Poison does not interrupt combat in any way.
  • If a poisoned monster goes out of combat (no longer trying to attack) the effect of poison is immediately removed from the monster.
  • The swamp lizard (salamander weapon) has a chance of inflicting poison equivalent to weapon poison++ when used in melee mode.

Trivia[edit | edit source]

  • Poison and venom are mutually exclusive, but it is possible to be poisoned or venomed and have disease at the same time, splitting your health orb in two to signify both applied effects.