Queen may refer to:
- Queen Efaritay, the legendary Icyene queen of Hallowvale.
- Queen Ellamaria, wife of King Roald.
- Fairy Queen, the ruler of Zanaris and the fairies, who is involved in the Fairy Tale quest series.
- Queen Glarial, a legendary elven queen married to the powerful king Baxtorian until her death and has a grandson named Islwyn.
- Ice Queen, resides under White Wolf Mountain and drops the ice gloves used in several quests, notably Heroes' Quest, Recipe for Disaster, and Desert Treasure.
- Kalphite Queen, a boss monster in the Kalphite Lair.
- Penance Queen, the boss monster of the Barbarian Assault minigame.
- The Queen of Thieves, a quest and NPC named eponymously as the alias of Lady Shauna Piscarilius.
- Sea Slug Queen, the main antagonist in the Sea Slug quest series.
- Sea Troll Queen, a quest boss monster who attacked the Piscatoris Fishing Colony along with her Sea Trolls during Swan Song.
- Queen Sigrid, the queen of the island of Etceteria.