Sanfew serum

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1 dose2 dose3 dose4 dose
Sanfew serum(1)
Sanfew serum(1).png
Released13 March 2007 (Update)
MembersYes
Quest itemNo
Properties
TradeableYes
EquipableNo
StackableNo
NoteableYes
OptionsDrink, Empty
DestroyDrop
ExamineA 1 dose Sanfew Serum.
Values
Value120 coins
High alch72 coins
Low alch48 coins
Weight0.02 kg
Grand Exchange
Exchange10,532 coins (info)
Buy limit2,000
Daily volume264
Loading...
Advanced data
Item ID10931
Sanfew serum(1) detail.png
Sanfew serum(2) detail.png
Sanfew serum(3) detail.png
Sanfew serum(4) detail.png

Sanfew serum combines the properties of super restore, superantipoison, and Relicym's balm potions (though, unlike the latter, will provide fifteen minutes of immunity to disease when consumed). The duration of the antipoison lasts six minutes, the same time as a superantipoison does. The restore value obtained per dose is 4 + 30% of the player's base level (round down) in each of the affected skills.

Sanfew serum is made by adding, in order, unicorn horn dust, clean snake weed and nail beast nails to an already made super restore. Partially completed Sanfew serums are called mixture - step 1 and step 2, but are not drinkable in these forms. Level 65 Herblore and completion of Zogre Flesh Eaters is required in order to make this potion.

96 Herblore experience is given for a completed 1-dose Sanfew serum, 128 experience for a 2-dose serum, 160 experience for a 3-dose serum and 192 experience for a 4-dose serum. Or more simply, the total experience given can be calculated with:

Sanfew serums can also be used on nail beasts, which can deal 20-40 damage per dose and grants melee experience. This requires the player to have no weapons equipped; if they do, it will automatically be unequipped if there is space in their inventory.

As Sanfew serums' higher price often makes super restores and prayer potions more cost efficient for restoring prayer, Sanfew serums are notably useful in situations where prayer restoration as well as poison protection are needed and inventory space is limited, such as Dagannoth Kings, as it fulfills the two requirements in one inventory space. Similarly, Sanfew serums are effective for fighting The Nightmare as they offer the same utility against parasites as Relicym's balm while also offering prayer restoration.

If a ring of the gods (i) or Prayer cape is equipped, or alternatively if a Prayer cape or holy wrench is in the player's inventory, the prayer restore increases to 4 + 32% of the player's current Prayer level, rounded down. This does not affect the rate of restoration of stats other than Prayer.

Effects[edit | edit source]

Stat restore is calculated with:

Skills Level Boost Skills Level Boost Skills Level Boost
1-3 +4 34-36 +14 67-69 +24
4-6 +5 37-39 +15 70-73 +25
7-9 +6 40-43 +16 74-76 +26
10-13 +7 44-46 +17 77-79 +27
14-16 +8 47-49 +18 80-83 +28
17-19 +9 50-53 +19 84-86 +29
20-23 +10 54-56 +20 87-89 +30
24-26 +11 57-59 +21 90-93 +31
27-29 +12 60-63 +22 94-96 +32
30-33 +13 64-66 +23 97-99 +33

If a ring of the gods (i) or Prayer cape is equipped, or alternatively if a Prayer cape or holy wrench is in the player's inventory, the amount of restored Prayer points is calculated with:

Skills Level Boost Skills Level Boost Skills Level Boost
1-3 +4 35-37 +15 69-71 +26
4-6 +5 38-40 +16 72-74 +27
7-9 +6 41-43 +17 75-78 +28
10-12 +7 44-46 +18 79-81 +29
13-15 +8 47-49 +19 82-84 +30
16-18 +9 50-53 +20 85-87 +31
19-21 +10 54-56 +21 88-90 +32
22-24 +11 57-59 +22 91-93 +33
25-28 +12 60-62 +23 94-96 +34
29-31 +13 63-65 +24 97-99 +35
32-34 +14 66-68 +25

Creation[edit | edit source]

The full creation process requires an untradeable ingredient, Snake weed, which can only found by searching marshy jungle vines south-west of Tai Bwo Wannai or as a drop from Jogres and Tribesmen.

Loading...
1 dose2 dose3 dose4 dose
Requirements
SkillLevelXP
Herblore Herblore65 (b)28.5
Quest points Partial completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Super restore(1).pngSuper restore(1)14,026
Unicorn horn dust.pngUnicorn horn dust1283
Total Cost4,309
Mixture - step 1(1).pngMixture - step 1(1)1N/A
Requirements
SkillLevelXP
Herblore Herblore65 (b)38
Quest points Partial completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Super restore(2).pngSuper restore(2)18,089
Unicorn horn dust.pngUnicorn horn dust1283
Total Cost8,372
Mixture - step 1(2).pngMixture - step 1(2)1N/A
Requirements
SkillLevelXP
Herblore Herblore65 (b)47.5
Quest points Partial completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Super restore(3).pngSuper restore(3)112,129
Unicorn horn dust.pngUnicorn horn dust1283
Total Cost12,412
Mixture - step 1(3).pngMixture - step 1(3)1N/A
Requirements
SkillLevelXP
Herblore Herblore65 (b)57
Quest points Partial completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Super restore(4).pngSuper restore(4)116,755
Unicorn horn dust.pngUnicorn horn dust1283
Total Cost17,038
Mixture - step 1(4).pngMixture - step 1(4)1N/A

Loading...
1 dose2 dose3 dose4 dose
Requirements
SkillLevelXP
Herblore Herblore65 (b)31.5
Quest points Partial completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Mixture - step 1(1).pngMixture - step 1(1)1N/A
Snake weed.pngSnake weed1N/A
Total Cost0
Mixture - step 2(1).pngMixture - step 2(1)1N/A
Requirements
SkillLevelXP
Herblore Herblore65 (b)42
Quest points Partial completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Mixture - step 1(2).pngMixture - step 1(2)1N/A
Snake weed.pngSnake weed1N/A
Total Cost0
Mixture - step 2(2).pngMixture - step 2(2)1N/A
Requirements
SkillLevelXP
Herblore Herblore65 (b)52.5
Quest points Partial completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Mixture - step 1(3).pngMixture - step 1(3)1N/A
Snake weed.pngSnake weed1N/A
Total Cost0
Mixture - step 2(3).pngMixture - step 2(3)1N/A
Requirements
SkillLevelXP
Herblore Herblore65 (b)63
Quest points Partial completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Mixture - step 1(4).pngMixture - step 1(4)1N/A
Snake weed.pngSnake weed1N/A
Total Cost0
Mixture - step 2(4).pngMixture - step 2(4)1N/A

Loading...
1 dose2 dose3 dose4 dose
Requirements
SkillLevelXP
Herblore Herblore65 (b)36
Quest points Completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Mixture - step 2(1).pngMixture - step 2(1)1N/A
Nail beast nails.pngNail beast nails122,537
Total Cost22,537
Sanfew serum(1).pngSanfew serum(1)110,532
Profit−12,005
Requirements
SkillLevelXP
Herblore Herblore65 (b)48
Quest points Completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Mixture - step 2(2).pngMixture - step 2(2)1N/A
Nail beast nails.pngNail beast nails122,537
Total Cost22,537
Sanfew serum(2).pngSanfew serum(2)122,034
Profit−503
Requirements
SkillLevelXP
Herblore Herblore65 (b)60
Quest points Completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Mixture - step 2(3).pngMixture - step 2(3)1N/A
Nail beast nails.pngNail beast nails122,537
Total Cost22,537
Sanfew serum(3).pngSanfew serum(3)132,365
Profit9,828
Requirements
SkillLevelXP
Herblore Herblore65 (b)72
Quest points Completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Mixture - step 2(4).pngMixture - step 2(4)1N/A
Nail beast nails.pngNail beast nails122,537
Total Cost22,537
Sanfew serum(4).pngSanfew serum(4)144,186
Profit21,649

Loading...
1 dose2 dose3 dose4 dose
Requirements
SkillLevelXP
Herblore Herblore65 (b)96
Quest points Completion of Zogre Flesh Eaters
Members
Member icon.png
TicksN/A
Materials
ItemQuantityCost
Super restore(1).pngSuper restore(1)14,026
Unicorn horn dust.pngUnicorn horn dust1283
Snake weed.pngSnake weed1N/A
Nail beast nails.pngNail beast nails122,537
Total Cost26,846
Sanfew serum(1).pngSanfew serum(1)110,532
Profit−16,314
Requirements
SkillLevelXP
Herblore Herblore65 (b)128
Quest points Completion of Zogre Flesh Eaters
Members
Member icon.png
TicksN/A
Materials
ItemQuantityCost
Super restore(2).pngSuper restore(2)18,089
Unicorn horn dust.pngUnicorn horn dust1283
Snake weed.pngSnake weed1N/A
Nail beast nails.pngNail beast nails122,537
Total Cost30,909
Sanfew serum(2).pngSanfew serum(2)122,034
Profit−8,875
Requirements
SkillLevelXP
Herblore Herblore65 (b)160
Quest points Completion of Zogre Flesh Eaters
Members
Member icon.png
TicksN/A
Materials
ItemQuantityCost
Super restore(3).pngSuper restore(3)112,129
Unicorn horn dust.pngUnicorn horn dust1283
Snake weed.pngSnake weed1N/A
Nail beast nails.pngNail beast nails122,537
Total Cost34,949
Sanfew serum(3).pngSanfew serum(3)132,365
Profit−2,584
Requirements
SkillLevelXP
Herblore Herblore65 (b)192
Quest points Completion of Zogre Flesh Eaters
Members
Member icon.png
TicksN/A
Materials
ItemQuantityCost
Super restore(4).pngSuper restore(4)116,755
Unicorn horn dust.pngUnicorn horn dust1283
Snake weed.pngSnake weed1N/A
Nail beast nails.pngNail beast nails122,537
Total Cost39,575
Sanfew serum(4).pngSanfew serum(4)144,186
Profit4,611

Price per dose[edit | edit source]

Item Price per dose
Sanfew serum(1).png Sanfew serum(1) 10,532
Sanfew serum(2).png Sanfew serum(2) 11,017
Sanfew serum(3).png Sanfew serum(3) 10,788
Sanfew serum(4).png Sanfew serum(4) 11,047

Item sources[edit | edit source]

Sanfew serum(4)[edit | edit source]

For an exhaustive list of all known sources for this item, see here (include RDT).
SourceLevelQuantityRarity
Coffin (Hallowed Sepulchre) HighN/A Casket.png1–21/10
Grand Hallowed CoffinN/A Casket.png1–21/10
Hallowed sackN/A Casket.png1–22 × 1/10
Kraken291 Multicombat.png24/128
Thermonuclear smoke devil301 Multicombat.png23/107
Vet'ion454 Multicombat.png10 (noted)5/128

Sanfew serum(3)[edit | edit source]

For an exhaustive list of all known sources for this item, see here (include RDT).
SourceLevelQuantityRarity
Phosani's Nightmare Multicombat.png6–125/100
The Nightmare814 Multicombat.png1–115/100

Shop locations[edit | edit source]

This list was created dynamically. For help, see the FAQ. To force an update of this list, click here.
SellerLocationNumber
in stock
Restock
time
Price
sold at
Price
bought at
Members?
~ Uglug's stuffsies ~Jiggig01m Coins 100.png 240Coins 100.png 144Member icon.png

Changes[edit | edit source]

Date Changes
15 April 2016
(update)

Half full potions could now be turned into bank placeholders.

7 April 2016
(update)

Drinking any kind of antipoison will no longer decrease your poison immunity.

1 May 2014
(update)

Sanfew serum is now correctly considered a potion rather than food when applying consumption delays and within the Duel Arena.