Sanfew serum

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1 dose2 dose3 dose4 dose
Sanfew serum(1)
Sanfew serum(1).png
Released13 March 2007 (Update)
MembersYes
Quest itemNo
Properties
TradeableYes
EquipableNo
StackableNo
NoteableYes
OptionsDrink, Empty
DestroyDrop
ExamineA 1 dose Sanfew Serum.
Values
Value120 coins
High alch72 coins
Low alch48 coins
Weight0.02 kg
Grand Exchange
Exchange8,063 coins (info)
Buy limit2,000
Daily volume5
Loading...
Advanced data
Item ID10931
Sanfew serum(1) detail.png
Sanfew serum(2) detail.png
Sanfew serum(3) detail.png
Sanfew serum(4) detail.png

Sanfew serum combines the properties of super restore, superantipoison, and Relicym's balm potions (though, unlike the latter, will provide fifteen minutes of immunity to disease when consumed). The duration of the antipoison lasts six minutes, the same time as a superantipoison does. The restore value obtained per dose is 4 + 30% of the player's base level (round down) in each of the affected skills.

Sanfew serum is made by adding, in order, unicorn horn dust, clean snake weed and nail beast nails to an already made super restore. Partially completed Sanfew serums are called mixture - step 1 and step 2, but are not drinkable in these forms. Level 65 Herblore and completion of Zogre Flesh Eaters is required in order to make this potion.

96 Herblore experience is given for a completed 1-dose Sanfew serum, 128 experience for a 2-dose serum, 160 experience for a 3-dose serum and 192 experience for a 4-dose serum. Or more simply, the total experience given can be calculated with:

Sanfew serums can also be used on nail beasts, which can deal 20-40 damage per dose and grants melee experience. This requires the player to have no weapons equipped; if they do, it will automatically be unequipped if there is space in their inventory.

As Sanfew serums' higher price often makes super restores and prayer potions more cost efficient for restoring prayer, Sanfew serums are notably useful in situations where prayer restoration as well as poison protection are needed and inventory space is limited, such as Dagannoth Kings, as it fulfills the two requirements in one inventory space. Similarly, Sanfew serums are effective for fighting The Nightmare as they offer the same utility against parasites as Relicym's balm while also offering prayer restoration.

If a ring of the gods (i) or Prayer cape is equipped, or alternatively if a Prayer cape or holy wrench is in the player's inventory, the prayer restore increases to 4 + 32% of the player's current Prayer level, rounded down. This does not affect the rate of restoration of stats other than Prayer.

Effects[edit | edit source]

Stat restore is calculated with:

Skills Level Boost Skills Level Boost Skills Level Boost
1-3 +4 34-36 +14 67-69 +24
4-6 +5 37-39 +15 70-73 +25
7-9 +6 40-43 +16 74-76 +26
10-13 +7 44-46 +17 77-79 +27
14-16 +8 47-49 +18 80-83 +28
17-19 +9 50-53 +19 84-86 +29
20-23 +10 54-56 +20 87-89 +30
24-26 +11 57-59 +21 90-93 +31
27-29 +12 60-63 +22 94-96 +32
30-33 +13 64-66 +23 97-99 +33

If a ring of the gods (i) or Prayer cape is equipped, or alternatively if a Prayer cape or holy wrench is in the player's inventory, the amount of restored Prayer points is calculated with:

Skills Level Boost Skills Level Boost Skills Level Boost
1-3 +4 35-37 +15 69-71 +26
4-6 +5 38-40 +16 72-74 +27
7-9 +6 41-43 +17 75-78 +28
10-12 +7 44-46 +18 79-81 +29
13-15 +8 47-49 +19 82-84 +30
16-18 +9 50-53 +20 85-87 +31
19-21 +10 54-56 +21 88-90 +32
22-24 +11 57-59 +22 91-93 +33
25-28 +12 60-62 +23 94-96 +34
29-31 +13 63-65 +24 97-99 +35
32-34 +14 66-68 +25

Creation[edit | edit source]

The full creation process requires an untradeable ingredient, Snake weed, which can only found by searching marshy jungle vines south-west of Tai Bwo Wannai or as a drop from Jogres and Tribesmen.

Loading...
1 dose2 dose3 dose4 dose
Requirements
SkillLevelXP
Herblore Herblore65 (b)28.5
Quest points Partial completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Super restore(1).pngSuper restore(1)13,707
Unicorn horn dust.pngUnicorn horn dust1274
Total Cost3,981
Mixture - step 1(1).pngMixture - step 1(1)1N/A
Requirements
SkillLevelXP
Herblore Herblore65 (b)38
Quest points Partial completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Super restore(2).pngSuper restore(2)17,417
Unicorn horn dust.pngUnicorn horn dust1274
Total Cost7,691
Mixture - step 1(2).pngMixture - step 1(2)1N/A
Requirements
SkillLevelXP
Herblore Herblore65 (b)47.5
Quest points Partial completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Super restore(3).pngSuper restore(3)111,234
Unicorn horn dust.pngUnicorn horn dust1274
Total Cost11,508
Mixture - step 1(3).pngMixture - step 1(3)1N/A
Requirements
SkillLevelXP
Herblore Herblore65 (b)57
Quest points Partial completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Super restore(4).pngSuper restore(4)115,256
Unicorn horn dust.pngUnicorn horn dust1274
Total Cost15,530
Mixture - step 1(4).pngMixture - step 1(4)1N/A

Loading...
1 dose2 dose3 dose4 dose
Requirements
SkillLevelXP
Herblore Herblore65 (b)31.5
Quest points Partial completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Mixture - step 1(1).pngMixture - step 1(1)1N/A
Snake weed.pngSnake weed1N/A
Total Cost0
Mixture - step 2(1).pngMixture - step 2(1)1N/A
Requirements
SkillLevelXP
Herblore Herblore65 (b)42
Quest points Partial completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Mixture - step 1(2).pngMixture - step 1(2)1N/A
Snake weed.pngSnake weed1N/A
Total Cost0
Mixture - step 2(2).pngMixture - step 2(2)1N/A
Requirements
SkillLevelXP
Herblore Herblore65 (b)52.5
Quest points Partial completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Mixture - step 1(3).pngMixture - step 1(3)1N/A
Snake weed.pngSnake weed1N/A
Total Cost0
Mixture - step 2(3).pngMixture - step 2(3)1N/A
Requirements
SkillLevelXP
Herblore Herblore65 (b)63
Quest points Partial completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Mixture - step 1(4).pngMixture - step 1(4)1N/A
Snake weed.pngSnake weed1N/A
Total Cost0
Mixture - step 2(4).pngMixture - step 2(4)1N/A

Loading...
1 dose2 dose3 dose4 dose
Requirements
SkillLevelXP
Herblore Herblore65 (b)36
Quest points Completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Mixture - step 2(1).pngMixture - step 2(1)1N/A
Nail beast nails.pngNail beast nails115,623
Total Cost15,623
Sanfew serum(1).pngSanfew serum(1)18,063
Profit−7,560
Requirements
SkillLevelXP
Herblore Herblore65 (b)48
Quest points Completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Mixture - step 2(2).pngMixture - step 2(2)1N/A
Nail beast nails.pngNail beast nails115,623
Total Cost15,623
Sanfew serum(2).pngSanfew serum(2)117,053
Profit1,430
Requirements
SkillLevelXP
Herblore Herblore65 (b)60
Quest points Completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Mixture - step 2(3).pngMixture - step 2(3)1N/A
Nail beast nails.pngNail beast nails115,623
Total Cost15,623
Sanfew serum(3).pngSanfew serum(3)125,301
Profit9,678[r 1]
  1. ^ Due to Grand Exchange prices changing based on trade volume, this profit may not be fully accurate if the components are infrequently traded.
Requirements
SkillLevelXP
Herblore Herblore65 (b)72
Quest points Completion of Zogre Flesh Eaters
Members
Member icon.png
Ticks2 (1.2s)
Materials
ItemQuantityCost
Mixture - step 2(4).pngMixture - step 2(4)1N/A
Nail beast nails.pngNail beast nails115,623
Total Cost15,623
Sanfew serum(4).pngSanfew serum(4)137,917
Profit22,294[r 1]
  1. ^ Due to Grand Exchange prices changing based on trade volume, this profit may not be fully accurate if the components are infrequently traded.

Loading...
1 dose2 dose3 dose4 dose
Requirements
SkillLevelXP
Herblore Herblore65 (b)96
Quest points Completion of Zogre Flesh Eaters
Members
Member icon.png
TicksN/A
Materials
ItemQuantityCost
Super restore(1).pngSuper restore(1)13,707
Unicorn horn dust.pngUnicorn horn dust1274
Snake weed.pngSnake weed1N/A
Nail beast nails.pngNail beast nails115,623
Total Cost19,604
Sanfew serum(1).pngSanfew serum(1)18,063
Profit−11,541
Requirements
SkillLevelXP
Herblore Herblore65 (b)128
Quest points Completion of Zogre Flesh Eaters
Members
Member icon.png
TicksN/A
Materials
ItemQuantityCost
Super restore(2).pngSuper restore(2)17,417
Unicorn horn dust.pngUnicorn horn dust1274
Snake weed.pngSnake weed1N/A
Nail beast nails.pngNail beast nails115,623
Total Cost23,314
Sanfew serum(2).pngSanfew serum(2)117,053
Profit−6,261
Requirements
SkillLevelXP
Herblore Herblore65 (b)160
Quest points Completion of Zogre Flesh Eaters
Members
Member icon.png
TicksN/A
Materials
ItemQuantityCost
Super restore(3).pngSuper restore(3)111,234
Unicorn horn dust.pngUnicorn horn dust1274
Snake weed.pngSnake weed1N/A
Nail beast nails.pngNail beast nails115,623
Total Cost27,131
Sanfew serum(3).pngSanfew serum(3)125,301
Profit−1,830
Requirements
SkillLevelXP
Herblore Herblore65 (b)192
Quest points Completion of Zogre Flesh Eaters
Members
Member icon.png
TicksN/A
Materials
ItemQuantityCost
Super restore(4).pngSuper restore(4)115,256
Unicorn horn dust.pngUnicorn horn dust1274
Snake weed.pngSnake weed1N/A
Nail beast nails.pngNail beast nails115,623
Total Cost31,153
Sanfew serum(4).pngSanfew serum(4)137,917
Profit6,764[r 1]
  1. ^ Due to Grand Exchange prices changing based on trade volume, this profit may not be fully accurate if the components are infrequently traded.

Price per dose[edit | edit source]

Item Price per dose
Sanfew serum(1).png Sanfew serum(1) 8,063
Sanfew serum(2).png Sanfew serum(2) 8,527
Sanfew serum(3).png Sanfew serum(3) 8,434
Sanfew serum(4).png Sanfew serum(4) 9,479

Item sources[edit | edit source]

Sanfew serum(4)[edit | edit source]

For an exhaustive list of all known sources for this item, see here (include RDT).
SourceLevelQuantityRarity
Coffin (Hallowed Sepulchre) HighN/A Casket.png1–21/10
Grand Hallowed CoffinN/A Casket.png1–21/10
Hallowed sackN/A Casket.png1–22 × 1/10
Kraken291 Multicombat.png24/128
Thermonuclear smoke devil301 Multicombat.png23/107
Vet'ion454 Multicombat.png10 (noted)5/128

Sanfew serum(3)[edit | edit source]

For an exhaustive list of all known sources for this item, see here (include RDT).
SourceLevelQuantityRarity
Phosani's Nightmare Multicombat.png6–125/100
The Nightmare814 Multicombat.png1–115/100

Shop locations[edit | edit source]

This list was created dynamically. For help, see the FAQ. To force an update of this list, click here.
SellerLocationNumber
in stock
Restock
time
Price
sold at
Price
bought at
Members?
~ Uglug's stuffsies ~Jiggig01m Coins 100.png 240Coins 100.png 144Member icon.png

Changes[edit | edit source]

Date Changes
15 April 2016
(update)

Half full potions could now be turned into bank placeholders.

7 April 2016
(update)

Drinking any kind of antipoison will no longer decrease your poison immunity.

1 May 2014
(update)

Sanfew serum is now correctly considered a potion rather than food when applying consumption delays and within the Duel Arena.