Smoke Blitz is the second highest level smoke spell in the Ancient Magicks spell book, and it requires a Magic level of 74. It is capable of hitting up to 23 damage (without any magic damage boosts) per cast.
Smoke Blitz is capable of poisoning a target at a 1/8 chance on hit, having a poison severity of 20 (where poison starts at 4 damage every 30 ticks or 18 seconds); this can be increased to 22 with an ancient sceptre. Increasing the total poison damage to 60 (first two hits does 5 damage), instead of 50.